Hydroxypropyl methylcellulose (HPMC) ndi hypromellose ndizomwe zimakhala zofanana, ndipo mawuwa amagwiritsidwa ntchito mosiyanasiyana. Awa ndi mayina ovuta amitundu yodziwika bwino ya ma polima opangidwa ndi cellulose omwe ali ndi ntchito zambiri m'mafakitale osiyanasiyana kuphatikiza mankhwala, zakudya ndi zodzola.
1. Kapangidwe kake ndi kapangidwe kake:
Hydroxypropylmethylcellulose (HPMC) ndikusintha kopangidwa kwa cellulose, polima wachilengedwe wopezeka m'makoma a cellulose. Kapangidwe kake ka HPMC kamapezeka poyambitsa magulu a hydroxypropyl ndi methyl pamaziko a cellulose. Gulu la hydroxypropyl limapangitsa kuti cellulose isungunuke kwambiri m'madzi, ndipo gulu la methyl limapangitsa kukhazikika kwake ndikuchepetsa kuyambiranso kwake.
2. Njira yopanga:
Kupanga kwa hydroxypropyl methylcellulose kumaphatikizapo kuchitira cellulose ndi propylene oxide kuyambitsa magulu a hydroxypropyl kenako ndi methyl chloride kuwonjezera magulu a methyl. Digiri ya m'malo (DS) ya hydroxypropyl ndi methyl imatha kusinthidwa panthawi yopanga, zomwe zimapangitsa kuti HPMC ikhale ndi magulu osiyanasiyana.
3. Katundu wathupi:
HPMC ndi ufa woyera mpaka pang'ono, wopanda fungo komanso wosakoma. Zake thupi katundu, monga mamasukidwe akayendedwe ndi solubility, zimadalira mlingo wa m'malo ndi molecular kulemera kwa polima. M'mikhalidwe yabwino, imasungunuka mosavuta m'madzi, ndikupanga njira yowonekera komanso yopanda mtundu.
4. Zolinga zachipatala:
Chimodzi mwazofunikira kwambiri za HPMC ndimakampani opanga mankhwala. Amagwiritsidwa ntchito kwambiri ngati mankhwala opangira mankhwala ndipo amagwira ntchito zosiyanasiyana pokonzekera mankhwala. HPMC imapezeka nthawi zambiri mumitundu yolimba yapakamwa monga mapiritsi, makapisozi, ndi mapiritsi. Zimagwira ntchito ngati binder, disintegrant, and controlled release agent, zomwe zimathandiza kuti pakhale bata komanso bioavailability ya mankhwalawa.
5. Udindo pakukonzekera kutulutsidwa koyendetsedwa:
Kuthekera kwa HPMC kupanga ma gels munjira zamadzimadzi kumapangitsa kuti ikhale yofunikira pakupanga mankhwala oyendetsedwa bwino. Posintha makulidwe ake komanso kupanga ma gel osakaniza, asayansi azachipatala amatha kuwongolera kuchuluka kwa zinthu zomwe zimagwira ntchito, potero amapeza mphamvu yokhalitsa komanso yayitali ya mankhwala.
6. Kugwiritsa ntchito m'makampani azakudya:
M'makampani azakudya, HPMC imagwiritsidwa ntchito ngati thickener, stabilizer ndi emulsifier. Imawongolera kapangidwe ka zakudya zosiyanasiyana, kuphatikiza sosi, soups ndi mkaka. Kuphatikiza apo, HPMC imagwiritsidwa ntchito pophika zakudya zopanda gilateni kupititsa patsogolo kapangidwe kake komanso kunyowa kwa zinthu zopanda gilateni.
7. Zomangamanga ndi zomangira:
HPMC imagwiritsidwa ntchito pantchito yomanga pazinthu monga zomatira matailosi, ma pulasitala opangidwa ndi simenti ndi zida za gypsum. Imawongolera kachulukidwe, kusunga madzi komanso zomatira pazinthu izi.
8. Zodzoladzola ndi zinthu zosamalira munthu:
Hypromellose ndi chinthu chodziwika bwino mu zodzoladzola komanso zinthu zosamalira anthu. Amagwiritsidwa ntchito mu zodzoladzola, mafuta odzola ndi ma shampoos chifukwa cha kukhuthala kwake komanso kukhazikika kwake. Kuphatikiza apo, zimathandizira kukonza kapangidwe kake komanso kumva kwa chinthucho.
9. Kupaka filimu muzamankhwala:
HPMC chimagwiritsidwa ntchito mu makampani mankhwala kwa filimu ❖ kuyanika mapiritsi. Mapiritsi okhala ndi filimu amapereka mawonekedwe abwino, kubisala kukoma komanso kuteteza kuzinthu zachilengedwe. Makanema a HPMC amapereka zokutira zosalala komanso zofananira, kuwongolera mtundu wonse wamankhwala.
13. Mapeto:
Hydroxypropyl methylcellulose (HPMC) ndi hypromellose amatanthauza polima yemweyo yemwe amagwiritsa ntchito pa cellulose yomwe imagwiritsidwa ntchito mosiyanasiyana muzamankhwala, chakudya, zodzoladzola, ndi zomangamanga. Makhalidwe ake apadera, monga kusungunuka, kukhazikika ndi biodegradability, amathandiza kuti agwiritsidwe ntchito kwambiri. Kusinthasintha kwa HPMC m'mafakitale osiyanasiyana kumawonetsa kufunikira kwake ngati zinthu zambiri, ndikupitilirabe.kusaka ndi chitukuko zitha kuwulula mapulogalamu owonjezera mtsogolo.
Izi mwachidule cholinga chake ndi kupereka kumvetsetsa kwatsatanetsatane kwa hydroxypropyl methylcellulose ndi hypromellose, kumveketsa kufunikira kwake m'magawo osiyanasiyana, ndikuwunikiranso gawo lawo popanga zinthu zambiri ndi mapangidwe.
Nthawi yotumiza: Dec-21-2023