Hydroxyethylcellulose (HEC) ndi polima yopanda ionic, yosungunuka m'madzi yochokera ku cellulose.Kapangidwe kake kapadera kamankhwala ndi kaphatikizidwe kake kamapangitsa kuti ikhale yosunthika yogwiritsidwa ntchito mosiyanasiyana m'mafakitale monga mankhwala, zodzoladzola, chakudya, ndi chisamaliro chamunthu.Chimodzi mwamakhalidwe ake odziwika bwino ndi mawonekedwe ake oyimitsidwa, omwe amagwira ntchito yofunika kwambiri pamapangidwe ambiri.
Kapangidwe ndi Katundu wa HEC
HEC imachokera ku cellulose, yomwe ndi polima yopezeka mwachilengedwe yomwe imapezeka m'makoma a cellulose.Kupyolera muzinthu zingapo zamakina, magulu a hydroxyethyl amalowetsedwa pamsana wa cellulose, zomwe zimapangitsa kuti pakhale polima wosungunuka m'madzi wokhala ndi zinthu zapadera.
Kapangidwe ka Chemical: Mapangidwe a cellulose amakhala ndi mayunitsi obwerezabwereza omwe amalumikizidwa ndi β-1,4-glycosidic bond.Mu HEC, magulu ena a hydroxyl (-OH) pamayunitsi a shuga amasinthidwa ndi magulu a hydroxyethyl (-OCH2CH2OH).Kulowetsedwaku kumapereka kusungunuka kwamadzi ku polima ndikusunga msana wa cellulose.
Kusungunuka kwamadzi: HEC imasungunuka kwambiri m'madzi, imapanga mayankho omveka bwino, owoneka bwino.Digiri ya m'malo (DS), yomwe imasonyeza kuchuluka kwa magulu a hydroxyethyl pamtundu uliwonse wa shuga, imakhudza kusungunuka kwa polima ndi zina.Kukwera kwa DS nthawi zambiri kumapangitsa kuti madzi asungunuke kwambiri.
Viscosity: Mayankho a HEC amasonyeza khalidwe la pseudoplastic, kutanthauza kuti kukhuthala kwawo kumachepa pansi pa kumeta ubweya wa ubweya.Katunduyu ndi wopindulitsa pamagwiritsidwe ntchito monga zokutira ndi zomatira, pomwe zinthuzo zimafunikira kuyenda mosavuta pakagwiritsidwe ntchito koma zimasunga mamasukidwe akamapuma.
Kupanga Mafilimu: HEC ikhoza kupanga mafilimu owonekera, osinthika akauma, kuwapangitsa kukhala oyenera kugwiritsidwa ntchito ngati wothandizira kupanga mafilimu muzinthu zosiyanasiyana.
Malipoti a malipoti a ndalama HEC
Kuyimitsidwa kumatanthauza kuthekera kwa zinthu zolimba kukhalabe omwazikana mkati mwa sing'anga yamadzimadzi popanda kukhazikika pakapita nthawi.HEC imawonetsa kuyimitsidwa kwabwino kwambiri chifukwa cha zinthu zingapo:
Kuthira ndi Kutupa: Tinthu tating'onoting'ono ta HEC tikamwazikana mumadzimadzi, timathira madzi ndikutupa, ndikupanga maukonde amitundu itatu omwe amatchera ndi kuyimitsa tinthu tolimba.Chikhalidwe cha hydrophilic cha HEC chimathandizira kuti madzi atengeke, zomwe zimapangitsa kuti kuchuluke kukhuthala komanso kukhazikika kwa kuyimitsidwa.
Particle Size Distribution: HEC imatha kuyimitsa mitundu yosiyanasiyana ya tinthu tating'ono chifukwa cha kuthekera kwake kupanga maukonde okhala ndi mauna osiyanasiyana.Izi kusinthasintha zimapangitsa kukhala oyenera suspending onse abwino ndi coarse particles zosiyanasiyana formulations.
Makhalidwe a Thixotropic: Mayankho a HEC amasonyeza khalidwe la thixotropic, kutanthauza kuti kukhuthala kwawo kumachepa pakapita nthawi pansi pa kumeta ubweya wokhazikika ndikuchira pamene kupanikizika kumachotsedwa.Katunduyu amalola kuthira kosavuta ndikugwiritsa ntchito kwinaku akusunga bata ndi kuyimitsidwa kwa tinthu tating'onoting'ono.
pH Kukhazikika: HEC imakhala yokhazikika pamitundu yambiri ya pH, ndikupangitsa kuti ikhale yoyenera kugwiritsidwa ntchito muzosakaniza za acidic, zandale, ndi zamchere popanda kusokoneza kuyimitsidwa kwake.
Kugwiritsa ntchito HEC mu Suspension Formulations
Kuyimitsidwa kwabwino kwa HEC kumapangitsa kuti ikhale yofunikira pazinthu zambiri m'mafakitale osiyanasiyana:
Utoto ndi Zopaka: HEC imagwiritsidwa ntchito ngati chowonjezera komanso choyimitsa mu utoto wamadzi ndi zokutira kuti mupewe kukhazikika kwa inki ndi zowonjezera.Makhalidwe ake a pseudoplastic amathandizira kugwiritsa ntchito bwino komanso kubisala kofanana.
Zopangira Zosamalira Munthu: Mu shamposi, zotsuka thupi, ndi zinthu zina zosamalira munthu, HEC imathandiza kuyimitsa zinthu zina monga zotulutsa, ma pigment, ndi mikanda yonunkhiritsa, kuonetsetsa kuti ngakhale kugawa ndi kukhazikika kwa mapangidwewo.
Mapangidwe a Mankhwala: HEC imagwiritsidwa ntchito poyimitsa mankhwala kuti ayimitse zosakaniza zomwe zimagwira ntchito ndikuwongolera kukhazikika komanso kukhazikika kwamitundu yamankhwala amadzimadzi.Kugwirizana kwake ndi ma API osiyanasiyana (Active Pharmaceutical Ingredients) ndi zowonjezera zimapangitsa kukhala chisankho chokondedwa kwa opanga ma formula.
Chakudya ndi Chakumwa: HEC imagwiritsidwa ntchito pazakudya monga mavalidwe a saladi, sosi, ndi zakumwa kuyimitsa zinthu zosasungunuka monga zitsamba, zonunkhira, ndi zamkati.Kusanunkhiza kwake komanso kusakoma kwake kumapangitsa kukhala koyenera kugwiritsidwa ntchito muzakudya popanda kukhudza zomverera.
Hydroxyethylcellulose (HEC) ndi polima wosunthika wokhala ndi mawonekedwe apadera oyimitsidwa, kupangitsa kuti ikhale yofunikira pamapangidwe osiyanasiyana m'mafakitale.Kutha kuyimitsa tinthu tating'onoting'ono mumayendedwe amadzimadzi, kuphatikiza ndi zina zofunika monga kusungunuka kwamadzi, kuwongolera kwa viscosity, komanso kukhazikika kwa pH, kumapangitsa kuti ikhale yofunikira kwa opanga omwe akufuna kupeza zinthu zokhazikika komanso zapamwamba.Pamene ntchito zofufuza ndi chitukuko zikupita patsogolo, ntchito za HEC pakuyimitsidwa zikuyembekezeka kuwonjezereka, kuyendetsa zatsopano ndi kupititsa patsogolo ntchito zamalonda m'magulu osiyanasiyana.
Nthawi yotumiza: May-09-2024