Kodi hypromellose acid imatsutsana?

Hypromellose, yomwe imadziwikanso kuti hydroxypropyl methylcellulose (HPMC), ndiyomwe imakhala yosamva acid. Komabe, kukana kwa asidi kwa hypromellose kumatha kukulitsidwa kudzera munjira zosiyanasiyana zopangira.

Hypromellose imasungunuka m'madzi koma imakhala yosasungunuka mu zosungunulira za organic ndi zakumwa zopanda polar. Chifukwa chake, m'malo okhala acidic, monga m'mimba, hypromellose imatha kusungunuka kapena kutupa pang'onopang'ono, kutengera zinthu monga kuchuluka kwa asidi, pH, komanso nthawi yowonekera.

Kuti muwonjezere kukana kwa asidi wa hypromellose muzopanga zamankhwala, njira zokutira za enteric nthawi zambiri zimagwiritsidwa ntchito. Zovala za Enteric zimagwiritsidwa ntchito pamapiritsi kapena makapisozi kuti awateteze ku chilengedwe cha acidic cha m'mimba ndikuwalola kuti apite kumalo osalowerera ndale a m'matumbo aang'ono asanatulutse zinthu zomwe zimagwira ntchito.

Zovala zamkati zimapangidwa kuchokera ku ma polima omwe amalimbana ndi asidi am'mimba, monga cellulose acetate phthalate (CAP), hydroxypropyl methylcellulose phthalate (HPMCP), kapena polyvinyl acetate phthalate (PVAP). Ma polima awa amapanga chotchinga chotchinga chozungulira piritsi kapena kapisozi, kuteteza kusungunuka msanga kapena kuwonongeka m'mimba.

Mwachidule, pamene hypromellose palokha siimalimbana ndi asidi, kukana kwake kwa asidi kumatha kupitilizidwa kudzera mu njira zopangira monga kupaka kwa enteric. Njirazi zimagwiritsidwa ntchito kwambiri popanga mankhwala kuti zitsimikizire kuperekedwa kwabwino kwa zinthu zomwe zimagwira ntchito pamalo omwe thupi likufuna kuchitapo kanthu.