Hydroxypropylmethylcellulose (HPMC) ndi chochokera ku cellulose chomwe chimagwiritsidwa ntchito m'mafakitale osiyanasiyana, kuphatikiza mankhwala, zomangamanga ndi zakudya. Kukhuthala kwake kumatha kusiyanasiyana kutengera zinthu monga kulemera kwa maselo, kuchuluka kwa m'malo, ndi ndende ya yankho.
Chiyambi cha Hydroxypropyl Methylcellulose (HPMC)
Hydroxypropyl methylcellulose ndi semi-synthetic polima yomwe imapezeka posintha ma cellulose. Chifukwa cha mawonekedwe ake apadera, amagwiritsidwa ntchito kwambiri ngati thickener, gelling agent, filimu yakale komanso stabilizer mu ntchito zosiyanasiyana.
Mapangidwe a mamolekyu ndi kapangidwe kake
HPMC imakhala ndi msana wa cellulose wokhala ndi hydroxypropyl ndi methoxy substituents. Digiri ya m'malo (DS) imatanthawuza kuchuluka kwa zolowa m'malo pa unit ya anhydroglucose mu tcheni cha cellulose. Mtengo weniweni wa DS umakhudza thupi ndi mankhwala a HPMC.
Kukhuthala kwa HPMC
Viscosity ndi gawo lofunikira la HPMC, makamaka pamapulogalamu omwe amagwiritsa ntchito kukhuthala kwake komanso kutulutsa ma gelling.
Kukhuthala kwa mayankho a HPMC kumakhudzidwa ndi zinthu zambiri:
1. Kulemera kwa mamolekyu
Kulemera kwa maselo a HPMC kumakhudza kukhuthala kwake. Nthawi zambiri, HPMCs yolemera kwambiri ya ma molekyulu imapanga mayankho apamwamba a viscosity. Pali magiredi osiyanasiyana a HPMC pamsika, iliyonse ili ndi mitundu yakeyake yolemetsa yama cell.
2. Digiri ya kusintha (DS)
Makhalidwe a DS a hydroxypropyl ndi magulu a methoxy amakhudza kusungunuka ndi kukhuthala kwa HPMC. Makhalidwe apamwamba a DS nthawi zambiri amapangitsa kuti madzi asungunuke kwambiri komanso kuti asungunuke kwambiri.
3. Kukhazikika
Kuchuluka kwa HPMC mu yankho ndi chinthu chofunikira chomwe chimakhudza kukhuthala. Pamene ndende ikuwonjezeka, kukhuthala kumawonjezeka. Ubale uwu nthawi zambiri umafotokozedwa ndi Krieger-Dougherty equation.
4. Kutentha
Kutentha kumakhudzanso kukhuthala kwa mayankho a HPMC. Nthawi zambiri, mamasukidwe akayendedwe amachepetsa pamene kutentha kumawonjezeka.
Malo ofunsira
Mankhwala: HPMC imagwiritsidwa ntchito kwambiri popanga mankhwala, kuphatikiza mapiritsi ndi njira zamaso, pomwe kumasulidwa koyendetsedwa ndi kukhuthala ndikofunikira.
Zomangamanga: M'makampani omanga, HPMC imagwiritsidwa ntchito ngati chokhuthala muzinthu zopangidwa ndi simenti kuti zitheke kugwira ntchito komanso kusunga madzi.
Makampani a Chakudya: HPMC imagwiritsidwa ntchito ngati thickener, stabilizer ndi emulsifier muzakudya.
Kukhuthala kwa hydroxypropyl methylcellulose ndi chinthu chovuta chomwe chimakhudzidwa ndi zinthu zingapo monga kulemera kwa maselo, kuchuluka kwa m'malo, ndende komanso kutentha. Makalasi osiyanasiyana a HPMC alipo kuti agwirizane ndi ntchito zina, ndipo opanga amapereka zidziwitso zaukadaulo zomwe zikuwonetsa kukhuthala kwa giredi iliyonse pansi pamikhalidwe yosiyanasiyana. Ofufuza ndi opanga ma formula ayenera kuganizira izi kuti agwirizane ndi zomwe HPMC ikufuna kukwaniritsa.
Nthawi yotumiza: Jan-20-2024