Chifukwa chiyani hypromellose imagwiritsidwa ntchito mu makapisozi?

Hypromellose, yomwe imadziwikanso kuti hydroxypropyl methylcellulose (HPMC), imagwiritsidwa ntchito kwambiri m'makapisozi pazifukwa zingapo:

1. Zamasamba / Zamasamba-Zamasamba: Makapisozi a Hypromellose amapereka njira ina yopangira makapisozi amtundu wa gelatin, omwe amachokera ku nyama. Makapisozi a Hypromellose ndi oyenera kwa anthu omwe amatsatira zakudya zamasamba kapena zamasamba, chifukwa amapangidwa kuchokera kuzinthu zopangira mbewu.
2. Biocompatibility: Hypromellose imachokera ku cellulose, polima wachilengedwe wopezeka m'makoma a cellulose. Chifukwa chake, ndi biocompatible ndipo nthawi zambiri imaloledwa bwino ndi thupi la munthu. Sichiwopsezo ndipo sichivulaza munthu akameza.
3. Kusungunuka kwamadzi: Makapisozi a Hypromellose amasungunuka mwachangu m'matumbo am'mimba, ndikutulutsa zomwe zili mkati kuti zilowe. Katunduyu amalola kuperekera koyenera kwa zosakaniza zogwira ntchito ndikuwonetsetsa kusungunuka kofanana kwa chipolopolo cha capsule.
4. Chitetezo cha Chinyezi: Ngakhale kuti makapisozi a hypromellose ndi osungunuka m'madzi, amapereka chitetezo ku chinyezi, zomwe zimathandiza kusunga bata ndi kukhulupirika kwa zomwe zili mkati. Izi ndizofunikira makamaka pazinthu za hygroscopic kapena zomwe sizimva chinyezi.
5. Kusintha Mwamakonda: Makapisozi a Hypromellose amapezeka mumitundu yosiyanasiyana komanso mitundu kuti agwirizane ndi milingo yosiyanasiyana komanso zokonda zamtundu. Zitha kusinthidwa kuti zigwirizane ndi zofunikira zenizeni za mankhwala ndi zosowa za wopanga.
6. Kugwirizana: Makapisozi a Hypromellose amagwirizana ndi mitundu yosiyanasiyana yamankhwala, kuphatikiza ufa, ma granules, pellets, ndi zakumwa. Iwo ndi oyenera encapsulating onse hydrophilic ndi hydrophobic zinthu, kupereka versatility mu chiphunzitso.
7. Kuvomerezeka Kwamalamulo: Makapisozi a Hypromellose avomerezedwa kuti agwiritsidwe ntchito muzamankhwala ndi zakudya zowonjezera ndi mabungwe owongolera monga US Food and Drug Administration (FDA), European Medicines Agency (EMA), ndi mabungwe ena olamulira padziko lonse lapansi. Amakwaniritsa miyezo yapamwamba yachitetezo, magwiridwe antchito, ndi machitidwe opanga.

Ponseponse, makapisozi a hypromellose amapereka maubwino angapo, kuphatikiza zokometsera zamasamba / zamasamba, biocompatibility, kusungunuka kwamadzi, kuteteza chinyezi, zosankha makonda, kugwirizana ndi mapangidwe osiyanasiyana, komanso kutsata malamulo. Izi zimawapangitsa kukhala chisankho chodziwika bwino pakuphatikiza mankhwala, zakudya zowonjezera, ndi zinthu zina.