Wothandizira Pharmaceutical
Hydroxypropyl methylcellulose (HPMC) ndi yoyera kapena yamkaka yoyera, yopanda fungo, yopanda kukoma, ufa wonyezimira kapena granule, kutaya thupi pa kuyanika sikudutsa 10%, kusungunuka m'madzi ozizira koma osati madzi otentha, pang'onopang'ono m'madzi otentha Kutupa, peptization, ndi kupanga viscous colloidal solution, yomwe imakhala yankho itakhazikika, ndipo imakhala gel ikatenthedwa. HPMC sisungunuka mu ethanol, chloroform ndi ether. Imasungunuka mu zosungunulira zosakanikirana za methanol ndi methyl chloride. Amasungunukanso mu zosungunulira zosakanikirana za acetone, methyl chloride ndi isopropanol ndi zosungunulira zina za organic. Njira yake yamadzimadzi imatha kulekerera mchere (njira yake ya colloidal siiwonongeka ndi mchere), ndipo pH ya 1% yamadzimadzi ndi 6-8. The molecular formula of HPMC ndi C8H15O8-(C10H18O6) -C815O, ndipo ma molecular molecular mass ndi pafupifupi 86,000.
HPMC ali kwambiri kusungunuka madzi m'madzi ozizira. Ikhoza kusungunuka mu njira yowonekera ndikugwedeza pang'ono m'madzi ozizira. M'malo mwake, imakhala yosasungunuka m'madzi otentha kuposa 60 ℃ ndipo imatha kutupa. Ndi non-ionic cellulose ether. Yankho lake liribe malipiro a ionic, samagwirizana ndi mchere wachitsulo kapena mankhwala a ionic organic, ndipo samachita ndi zipangizo zina panthawi yokonzekera; ali ndi mphamvu zotsutsana ndi matupi awo sagwirizana, ndipo ndi kuwonjezeka kwa mlingo wa kulowetsedwa m'malo mwa maselo, ake Ndiwogonjetsedwa ndi ziwengo komanso okhazikika; imakhalanso ndi vuto la metabolic. Monga chothandizira chamankhwala, sichimapangidwa ndi metabolized kapena kutengeka. Choncho, sapereka zopatsa mphamvu mu mankhwala ndi zakudya. Ndikalori wochepa, wopanda mchere, komanso wopanda mchere kwa odwala matenda ashuga. Matupi mankhwala ndi zakudya ndi applicability wapadera; imakhala yokhazikika kwa ma acid ndi alkalis, koma ngati mtengo wa PH umaposa 2 ~ 11 ndipo umakhudzidwa ndi kutentha kwapamwamba kapena uli ndi nthawi yayitali yosungirako, kukhuthala kwake kudzachepa; yankho lake lamadzimadzi limatha kupereka zochitika zapamtunda, kuwonetsa kugwedezeka kwapang'onopang'ono komanso kupsinjika kwapakati; ili ndi emulsification yogwira ntchito pazigawo ziwiri, ingagwiritsidwe ntchito ngati stabilizer yothandiza komanso yoteteza colloid; yankho lake lamadzimadzi lili ndi zinthu zabwino kwambiri zopangira filimu, ndi piritsi ndi piritsi. Chophimba cha filimu chopangidwa ndi icho chimakhala ndi ubwino wa colorlessness ndi kulimba. Kuwonjezera glycerin kungathandizenso pulasitiki yake.
Zogulitsa za QualiCell HPMC zitha kusintha mwazinthu zotsatirazi mu Pharmaceutical Excipient:
· Ikasungunuka m'madzi ndi kusungunuka kudzera mu zosungunulira, HPMC imapanga filimu yowonekera yokhala ndi mphamvu zambiri.
· Kumawonjezera mphamvu yomanga.
· Hydrophilic matrix yogwiritsidwa ntchito limodzi ndi ma HPMC hydrates kupanga gel wosanjikiza, kuwongolera njira yotulutsa mankhwala.
| Gulu lalangizidwa: | Funsani TDS |
| Chithunzi cha HPMC60AX5 | Dinani apa |
| Chithunzi cha HPMC60AX15 | Dinani apa |