Kodi hypromellose imakhala ndi zotsatirapo ziti?

Hypromellose, yomwe imadziwikanso kuti hydroxypropyl methylcellulose (HPMC), nthawi zambiri imawonedwa ngati yotetezeka kuti igwiritsidwe ntchito muzamankhwala, zakudya, zodzola, ndi zina.Amagwiritsidwa ntchito kwambiri ngati thickening agent, emulsifier, stabilizer, ndi kupanga mafilimu chifukwa cha biocompatibility, kawopsedwe kochepa, komanso kusowa kwa allergenicity.Komabe, nthawi zina, anthu amatha kukumana ndi zotsatira zoyipa kapena zoyipa akamagwiritsa ntchito mankhwala okhala ndi hypromellose.Zotsatira zoyipa za hypromellose ndi izi:

1. Kusapeza bwino kwa m'mimba: Kwa anthu ena, makamaka akamamwa kwambiri, hypromellose ingayambitse m'mimba kusapeza bwino monga kuphulika, mpweya, kapena kutsegula m'mimba pang'ono.Izi ndizofala kwambiri pamene hypromellose imagwiritsidwa ntchito pa mlingo waukulu m'mapangidwe a mankhwala kapena zakudya zowonjezera zakudya.
2. Thupi lawo siligwirizana: Ngakhale ndizosowa, hypersensitivity zimachitikira hypromellose zikhoza kuchitika mwa anthu tcheru.Zizindikiro za ziwengo zitha kukhala zotupa pakhungu, kuyabwa, kutupa, kapena kupuma movutikira.Anthu omwe ali ndi ziwengo zodziwika bwino za cellulose kapena mankhwala ogwirizana nawo ayenera kupewa zinthu zomwe zili ndi hypromellose.
3. Kupweteka kwa maso: Hypromellose imagwiritsidwanso ntchito pokonzekera maso monga madontho a maso ndi mafuta odzola.Nthawi zina, munthu amatha kupsa mtima kwakanthawi, kuyaka, kapena kumva kuluma akagwiritsidwa ntchito.Izi nthawi zambiri zimakhala zofatsa ndipo zimatha zokha.
4. Kusokonekera kwa mphuno: Hypromellose nthawi zina amagwiritsidwa ntchito popopera mphuno ndi njira zothirira m'mphuno.Anthu ena amatha kutsekeka m'mphuno kwakanthawi kapena kupsa mtima atagwiritsa ntchito mankhwalawa, ngakhale izi sizachilendo.
5. Kuyanjana kwa mankhwala: Popanga mankhwala, hypromellose imatha kuyanjana ndi mankhwala ena, zomwe zimakhudza kuyamwa kwawo, bioavailability, kapena mphamvu.Anthu omwe amamwa mankhwala akuyenera kukaonana ndi dokotala kapena wamankhwala asanagwiritse ntchito mankhwala okhala ndi hypromellose kuti apewe kuyanjana ndi mankhwala.

Ndikofunika kuzindikira kuti anthu ambiri amalekerera bwino hypromellose, ndipo zotsatira zake zimakhala zochepa ndipo nthawi zambiri zimakhala zochepa.Komabe, ngati mukukumana ndi zizindikiro zachilendo kapena zoopsa mutagwiritsa ntchito mankhwala omwe ali ndi hypromellose, siyani kugwiritsa ntchito ndipo funsani kuchipatala mwamsanga.Monga chopangira chilichonse, ndikofunikira kugwiritsa ntchito zinthu zomwe zili ndi hypromellose molingana ndi mlingo wovomerezeka ndi malangizo operekedwa ndi wopanga kapena katswiri wazachipatala.