Hydroxypypyl methylcellulose (hpmc) ndi yosiyanasiyana ndipo poizoni wogwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana, omwe amadziwika ndi ntchito zake zapadera. Patsamba ili ndikuchokera ku cellulose, polymer yachilengedwe imapezeka mu khoma la maselo. Kuti mumvetsetse kapangidwe ka hydrobypropylmelose, ndikofunikira kuti muchepetse kapangidwe kake ndi kaphatikizidwe ka cellulose iyi.
Kapangidwe ka cellulose:
Cellulose ndi chakudya chovuta chophatikizika chokhala ndi mzere wa mzere wa β-d-glucose olumikizidwa ndi β-1,4-glycosidic. Ma unyolo awa a glucose amakhala limodzi ndi ma hydrogen kuti apange mawonekedwe okhazikika. Cellulose ndiye gawo lalikulu lazomera zobzala makhoma, ndikupatsa mphamvu komanso kumangiriza kubzala maselo.
Zowonongeka za hydroxypropyl methylcellulose:
Hydroxypylropyl imapangidwa ndi mankhwala osintha mwa mitundu ya ma hydroxypropyl ndi methyl m'magulu akulu a cellulose. Kupanga nthawi zambiri kumaphatikizapo izi:
Kutengera Kwakufuna:
Methylation: Kuchita cellulose ndi methyl yankho la alkalinide kubweretsa methl magulu (-ch3) m'magulu a hydroxyl.
Hydroxypropropropropropropylation: methylated celulolose zokhudzana ndi Propylene oxide kuyambitsa magulu a hydroxypyl (-ch2chohch3) mu ma cellulose. Izi zimawonjezera kusungunuka kwamadzi ndikusintha zinthu zakuthupi za cellulose.
Kuyeretsa:
Direlose yosinthidwa imatsukidwa kuti ichotse zowongolera zilizonse zosafunikira, zopangidwa ndi zinthu zina.
Kuyanika ndi kupera:
Ma hydroxypropyll methylcellulose imawuma ndikuyika mu ufa wabwino wokonzekera kugwiritsa ntchito zinthu zosiyanasiyana.
Zosakaniza za hydroxypropyl methylcellulose:
Kupanga kwa hydroxypropyll methylcellulose kumadziwika ndi kuchuluka kwa malo olowa m'malo omwe ma hydroxypropyl ndi methyl amasinthira magulu a hydroxyl mu unyolo wa cydroxyy. Magawo osiyanasiyana a HPMC ali ndi madigiri osiyanasiyana azolowa m'malo, akukhudza kusungunuka kwawo, mamasukidwe ndi zina.
Njira ya mankhwala a hydroxypypyl amatha kufotokozedwa ngati (C6H7O2 (O) 3-MN) m (oh) _x, pomwe zikuyimira kuchuluka kwa zolowa m'malo.
M: digiri ya methylation (magulu a methyl pa unit ya glucose)
n: digiri ya hydroxypropropropropropy (hydroxypyl magulu pa gawo la glucose)
x: Chiwerengero cha mayunitsi a shuga mu cellulose unyolo
Mawonekedwe ndi ntchito:
Kusungunuka: HPMC ndi kusungunuka kwamadzi, ndipo kuchuluka kwa zogwirizira kumakhudza mawonekedwe ake. Imapanga yankho lomveka bwino komanso lowoneka m'madzi, ndikupangitsa kukhala koyenera kwa mitundu yosiyanasiyana.
Ma Isccess: Mawonekedwe a HPMC yankho la HPMC limadalira zinthu monga kulemera kwa ma celecular ndi digiri ya cholowa m'malo mwake. Katunduyu ndi wofunikira kwambiri pantchito monga mankhwala opangira mankhwala omwe amafunikira mapangidwe omasulidwa.
Mapangidwe a filimu: HPMC imatha kupanga mafilimu oonda monga yankho limawuma, kupangitsa kuti ikhale yothandiza pakupanga mankhwala, chakudya ndi mafakitale ena.
Kukhazikika ndi Otsatsa: Makampani ogulitsa zakudya, hpmc amagwiritsidwa ntchito ngati thickir ndi okhazikika pazogulitsa zosiyanasiyana, kuphatikizapo msuzi, zakudya, mafuta owiritsa.
Zogwiritsa ntchito mankhwala: HPMC imagwiritsidwa ntchito kwambiri pamitundu yamankhwala, kuphatikiza mapiritsi, makapisozi, ndi ophthalmic njira, chifukwa cha kumasulidwa kwake ndi zinthu zopanda pake.
Ntchito ndi Zovala: HPMC imagwiritsidwa ntchito pomanga monga matope, zomata za matabwa ndi ziphuphu. Amagwiritsidwanso ntchito ngati thickir ndi okhazikika pa utoto ndi zokutira.
Zogulitsa Zaumwini: Mu zodzikongoletsera komanso makampani ogulitsa patokha, hpmc imapezeka muzogulitsa monga zonona, zotupa ndi shampoos, komwe zimapereka mawonekedwe ndi kukhazikika.
Hydroxypropyll methylcellulose imapezeka ndi methylation ndi hydroxyproproproproproplation ya cellulose. Ndicholinga cha polymer ambiri ndi mitundu yosiyanasiyana. Malo ake apadera amapangitsa kukhala ofunika m'mafakitale monga mankhwala, chakudya, zomanga ndi chisamaliro chaumwini. Kusintha kwa kusintha kwa cellulose kumatha kukhala bwino kwambiri katundu wa HPMC, ndikupangitsa kukhala chinthu chofunikira kwambiri pazogulitsa zathu zatsiku ndi tsiku.
Post Nthawi: Jan-10-2024