Hydroxypropyl methylcellulose (HPMC) ndi polima wosunthika komanso wogwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana, omwe amadziwika chifukwa cha mawonekedwe ake apadera komanso ntchito zake.Pagululi ndi lochokera ku cellulose, polima wachilengedwe wopezeka m'makoma a cellulose.Kuti mumvetsetse kapangidwe ka hydroxypropylmethylcellulose, ndikofunikira kuyang'ana kapangidwe kake ndi kaphatikizidwe ka cellulose iyi.
Kapangidwe ka cellulose:
Cellulose ndi kagayidwe kachabechabe kamene kamapangidwa ndi mzere wozungulira wa mayunitsi a β-D-glucose olumikizidwa ndi β-1,4-glycosidic bond.Maunyolo a shuga awa amalumikizidwa pamodzi ndi ma hydrogen bond kuti apange mzere wokhazikika.Cellulose ndiye chigawo chachikulu cha makoma a cell cell, kupereka mphamvu ndi kusasunthika kwa ma cell.
Zotsatira za Hydroxypropyl Methylcellulose:
Hydroxypropyl methylcellulose amapangidwa posintha ma cellulose ndikuyambitsa magulu a hydroxypropyl ndi methyl mumagulu akulu a cellulose.Kupanga nthawi zambiri kumakhala ndi izi:
Etherification reaction:
Methylation: Kuchiza cellulose ndi njira ya alkaline ndi methyl chloride kuyambitsa magulu a methyl (-CH3) m'magulu a hydroxyl (-OH) a cellulose.
Hydroxypropylation: Ma cellulose a methylated amakumananso ndi propylene oxide kuti apangitse magulu a hydroxypropyl (-CH2CHOHCH3) mu cellulose.Izi zimawonjezera kusungunuka kwamadzi ndikusintha mawonekedwe a cellulose.
kuyeretsedwa:
Ma cellulose osinthidwa ndiye amayeretsedwa kuti achotse ma reagents aliwonse osakhudzidwa, zopangidwa ndi zinthu kapena zonyansa.
Kuyanika ndi kupera:
Hydroxypropyl methylcellulose yoyeretsedwa imawumitsidwa ndikuphwanyidwa kukhala ufa wabwino wokonzeka kugwiritsidwa ntchito mosiyanasiyana.
Zosakaniza za Hydroxypropyl Methylcellulose:
Kupangidwa kwa hydroxypropyl methylcellulose kumadziwika ndi kuchuluka kwa m'malo, komwe kumatanthawuza momwe magulu a hydroxypropyl ndi methyl amalowetsa magulu a hydroxyl mu unyolo wa cellulose.Osiyana magiredi a HPMC ndi madigiri osiyana m'malo, zimakhudza solubility awo, mamasukidwe akayendedwe ndi katundu wina.
Mankhwala a hydroxypropyl methylcellulose amatha kufotokozedwa ngati (C6H7O2(OH)3-mn(OCH3)m(OCH2CH(OH)CH3)n)_x,pamene m ndi n imayimira digiri ya kulowetsedwa.
m: digiri ya methylation (magulu a methyl pa gawo la shuga)
n: digiri ya hydroxypropylation (magulu a hydroxypropyl pa yuniti ya shuga)
x: kuchuluka kwa mayunitsi a shuga mu tcheni cha cellulose
Mawonekedwe ndi Mapulogalamu:
Kusungunuka: HPMC imasungunuka m'madzi, ndipo kuchuluka kwa m'malo kumakhudzanso kusungunuka kwake.Amapanga yankho lomveka bwino komanso lowoneka bwino m'madzi, ndikupangitsa kuti likhale loyenera kupanga mitundu yosiyanasiyana.
Viscosity: Kukhuthala kwa yankho la HPMC kumadalira zinthu monga kulemera kwa maselo ndi kuchuluka kwa m'malo.Katunduyu ndi wofunikira kwambiri pamagwiritsidwe ntchito ngati mankhwala omwe amafunikira njira zowongolera zotulutsa.
Kupanga Mafilimu: HPMC imatha kupanga mafilimu opyapyala pamene yankho likuuma, ndikupangitsa kuti ikhale yothandiza pakupaka m'mafakitale amankhwala, chakudya ndi zina.
Ma Stabilizers and Thickeners: M'makampani azakudya, HPMC imagwiritsidwa ntchito ngati chowonjezera komanso chokhazikika pazinthu zosiyanasiyana, kuphatikiza ma sauces, maswiti, ndi zinthu zophika.
Kugwiritsa Ntchito Mankhwala: HPMC imagwiritsidwa ntchito kwambiri popanga mankhwala, kuphatikiza mapiritsi, makapisozi, ndi mayankho amaso, chifukwa chakuwongolera kwake kumasulidwa komanso kuyanjana kwachilengedwe.
Kumanga ndi zokutira: HPMC imagwiritsidwa ntchito pomanga zinthu monga matope, zomatira matailosi ndi pulasitala.Amagwiritsidwanso ntchito ngati thickener ndi stabilizer mu utoto ndi ❖ kuyanika formulations.
Zopangira Zosamalira Munthu: M'makampani opanga zodzoladzola ndi chisamaliro chamunthu, HPMC imapezeka muzinthu monga mafuta opaka, mafuta odzola ndi ma shampoos, komwe imapereka mawonekedwe komanso kukhazikika.
Hydroxypropyl methylcellulose imapezeka ndi methylation ndi hydroxypropylation ya cellulose.Ndi ma polima amitundu yambiri omwe amagwiritsidwa ntchito mosiyanasiyana.Makhalidwe ake apadera amachititsa kuti ikhale yamtengo wapatali m'mafakitale monga mankhwala, chakudya, zomangamanga ndi chisamaliro chaumwini.Kusintha koyendetsedwa kwa cellulose kumatha kukonza bwino zinthu za HPMC, ndikupangitsa kuti ikhale gawo lofunikira pazinthu zambiri zomwe timakumana nazo pamoyo wathu watsiku ndi tsiku.
Nthawi yotumiza: Jan-10-2024